Comparison of vascular growth factors in the murine brain reveals placenta growth factor as prime candidate for CNS revascularization-Reference-Cited by-同舟云学术

Comparison of vascular growth factors in the murine brain reveals placenta growth factor as prime candidate for CNS revascularization

Published:2013-08-01 Issue:5 Volume:122 Page:658-665
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Gaál Emília Ilona¹²,Tammela Tuomas¹,Anisimov Andrey¹,Marbacher Serge²,Honkanen Petri²,Zarkada Georgia¹,Leppänen Veli-Matti¹,Tatlisumak Turgut³,Hernesniemi Juha²,Niemelä Mika²,Alitalo Kari¹

Affiliation:

1. Wihuri Research Institute and Translational Cancer Biology Program, Faculty of Medicine, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland; and

2. Department of Neurosurgery and

3. Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland

Abstract

Key Points AAV-mediated gene transfer of vascular growth factors. Among 7 endothelial growth factors, PlGF has optimal properties for induction of new vessel growth without vascular leakage or inflammation in the brain.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/5/658/1374720/658.pdf

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