1. From the Molecular/Cancer Biology Laboratory (A. Anisimov, J.S., S.K., V.-M.L., M.J., K.A.), Biomedicum Helsinki, Department of Pathology, Haartman Institute and Helsinki University Central Hospital, University of Helsinki, Finland; and Department of Biotechnology and Molecular Medicine (A. Alitalo, P.K., S.Y.-H.), A. I. Virtanen Institute for Molecular Sciences, University of Kuopio, Finland.