How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?

Author:

Cong Vu Thanh12ORCID,Houng Jacinta L.12ORCID,Kavallaris Maria234ORCID,Chen Xin5ORCID,Tilley Richard D.1ORCID,Gooding J. Justin12ORCID

Affiliation:

1. School of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia

2. Australian Centre for NanoMedicine, University of New South Wales, Sydney, NSW 2052, Australia

3. Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW 2052, Australia

4. School of Clinical Medicine, UNSW Medicine & Health, University of New South Wales, Sydney, NSW 2052, Australia

5. School of Chemical Engineering and Technology, Shaanxi Key Laboratory of Energy Chemical Process Intensification, Institute of Polymer Science in Chemical Engineering, Xi’an Jiao Tong University, Xi’an, China

Abstract

Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs into the diseased cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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