Intracellular self-aggregation of biomimetic Fe3O4 nanoparticles for enhanced ferroptosis-inducing therapy of breast cancer

Author:

Zhang Zhendong1,Xie Beibei2ORCID,Lu Xiaojie1,Xiong Lishan1,Li Xinyuan1,Zhang Yan1,Li Chunlai2,Wang Chenhui1ORCID

Affiliation:

1. Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Innovative Drug Research Center, School of Pharmaceutical Sciences, Chongqing University, 55 South Daxuecheng Road, Chongqing 401331, P. R. China

2. Department of Liver Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai Engineering Research Center of Transplantation and Immunology, Shanghai 200127, China

Abstract

A supramolecular and cell membrane co-modified drug delivery system was constructed to enhance Fe3O4 and SAS synergistically induced ferroptosis anti-tumor therapy.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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