Functional CYP3A variants affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,Genetics,Molecular Medicine
Link
http://www.nature.com/articles/s41397-021-00216-w.pdf
Reference43 articles.
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2. Tang JT, Yan L, Wang LL, Bai YJ, Li YM, Zou YG, et al. A low fixed tacrolimus starting dose is effective and safe in Chinese renal transplantation recipients. Ann Transpl. 2018;23:300–9.
3. Ekberg H, Tedesco-Silva H, Demirbas A, Vitko S, Nashan B, Gurkan A, et al. Reduced exposure to calcineurin inhibitors in renal transplantation. N. Engl J Med. 2007;357:2562–75.
4. Vanhove T, Annaert P, Kuypers DR. Clinical determinants of calcineurin inhibitor disposition: a mechanistic review. Drug Metab Rev. 2016;48:88–112.
5. Kamdem LK, Streit F, Zanger UM, Brockmoller J, Oellerich M, Armstrong VW, et al. Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus. Clin Chem. 2005;51:1374–81.
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1. Impact of genetic polymorphisms on tacrolimus trough blood concentration in Chinese liver transplant recipients;Pharmacogenomics;2023-03
2. Transcription Factors and ncRNAs Associated with CYP3A Expression in Human Liver and Small Intestine Assessed with Weighted Gene Co-Expression Network Analysis;Biomedicines;2022-11-28
3. Regulatory variants in a novel distal enhancer regulate the expression of CYP3A4 and CYP3A5;Clinical and Translational Science;2022-09-20
4. Genomewide association study identifies a novel variant associated with tacrolimus trough concentration in Chinese renal transplant recipients;Clinical and Translational Science;2022-08-28
5. Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients;Biomedicine & Pharmacotherapy;2022-01
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