Analytical characterization and antimicrobial properties of novel copper nanoparticle–loaded electrosynthesized hydrogel coatings

Author:

Cometa Stefania1,Iatta Roberta2,Ricci Maria Antonietta3,Ferretti Concetta4,De Giglio Elvira5

Affiliation:

1. Jaber Innovation s.r.l., Rome, Italy

2. Department of Biomedical Sciences and Human Oncology, University of Bari “Aldo Moro,” Bari, Italy

3. Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari “Aldo Moro,” Bari, Italy

4. Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy

5. Department of Chemistry, University of Bari “Aldo Moro,” Bari, Italy

Abstract

In this study, a novel antimicrobial coating was developed to avoid infections and to provide sterile conditions for stainless steel devices. Poly(ethylene glycol diacrylate) hydrogel thin films were modified with copper-based nanoparticles, following two different entrapment procedures. These coatings were firmly attached on metal substrates by means of a simple and fast electrochemical polymerization technique. The surface composition of the Cu nanoparticles–modified hydrogel coatings and their bactericidal effect against Staphylococcus aureus and Escherichia coli was studied, and the efficacy of such systems in preventing bacterial infections demonstrated.

Publisher

SAGE Publications

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

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