Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis-Reference-Cited by-同舟云学术

Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis

Published:2009-04-23 Issue:5 Volume:15 Page:644-646
ISSN:1352-4585
Container-title:Multiple Sclerosis Journal
language:en
Short-container-title:Mult Scler

Author:

Liang J¹,Zhang H¹,Hua B¹,Wang H¹,Wang J²,Han Z²,Sun L¹

Affiliation:

1. Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China

2. Institute of Hematology, CAMS & PUMC, Tianjing 300020, P. R. China

Abstract

Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system. Umbilical cord derived mesenchymal stem cells are immunosuppressive. We transplanted mesenchymal stem cells in a patient with refractory progressive MS, and the disease course was stabilized after the transplantation. We postulate that mesenchymal stem cells have a potent immunosuppressive effect in vivo.

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1352458509104590

Reference5 articles.

1. Human mesenchymal stem cells modulate allogeneic immune cell responses

2. Interactions Between Human Mesenchymal Stem Cells and Natural Killer Cells

3. Differences in mesenchymal stem cell cytokine profiles between MS patients and healthy donors: Implication for assessment of disease activity and treatment

4. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells

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