Affiliation:
1. Keio Cancer Center , Keio University Hospital, School of Medicine, Tokyo, Japan
2. Department of Frontier Surgery , Graduate School of Medicine, Chiba University, Chiba, Japan
3. Department of Head and Neck , Esophageal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan
4. Department of Surgery , Keio University School of Medicine, Tokyo, Japan
Abstract
AbstractThis review focuses on the treatment about elderly esophageal cancer to clarify the current situation regarding our clinical question. Although there are several reviews about elderly esophageal cancer treatment, there are fundamental differences between Japan and the rest of the world. Two main differences are raised: histological differences and treatment strategies for resectable patients. We overview each status according to following clinical questions. First, there are no established evaluation criteria for frail. Second, selection criteria for surgery or non-surgery are not established. Third, few specific treatments for elderly patients (EPs) are investigated. In conclusion, there are many reports about treatment of esophageal squamous cell carcinoma for EPs, although treatment strategy is still controversial. We have to consider well-designed prospective trial to confirm specific treatment strategy according to each stage.
Funder
Chugai Pharmaceutical Company, Ltd
Taiho Pharmaceutical Company, Ltd
Fujifilm, Toyama Chemical Company, Ltd
Abbott Japan Company, Ltd
KCI Licensing, Inc
Tsumura & Company, Ltd
Sanofi K.K., Eisai Company, Ltd
Japan Blood Products Organization Medtronic Japan Company, Ltd
Nihon Pharmaceutical Company, Ltd
Ono Pharmaceutical Company, Ltd
Pfizer Japan, Inc
Kyouwa Hakkou Kirin Company, Ltd
Taisho Toyama Pharmaceutical Company, Ltd
Dainippon Sumitomo Pharma Company, Ltd
Medicon, Inc
Astellas Pharma, Inc
Kowa Pharmaceutical Company, Ltd
Kaken Pharmaceutical Company, Ltd
Shionogi Company, Ltd
Otsuka Pharmaceutical Factory, Inc
Takeda Pharmaceutical Company, Ltd
Otsuka Pharmaceutical Company, Ltd
EA Pharma Company, Ltd
Asahi Kasei Company, Ltd
Merck Serono Company, Ltd
Daiichi Sankyo Company, Ltd
Yakult Honsha Company, Ltd
Nihon Pharmaceutical Co, Ltd
Ono Pharmaceutical Company
Taisho Toyama Pharmaceutical Company
Publisher
Oxford University Press (OUP)
Subject
Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology,General Medicine