Untangling the crosstalk between BRCA1 and R-loops during DNA repair
Author:
Affiliation:
1. Leiden University Medical Center, Department of Human Genetics, Leiden, The Netherlands
2. Oncode Institute, Utrecht, The Netherlands
Abstract
Funder
NWO
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/49/9/4848/37997366/gkab178.pdf
Reference189 articles.
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3. DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner;Collins;Nat. Commun.,2020
4. Loop extrusion as a mechanism for formation of DNA damage repair foci;Arnould;Nature,2021
5. PARP inhibitor resistance: a tug-of-war in BRCA-mutated cells;Noordermeer;Trends Cell Biol.,2019
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1. PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity;Nature Communications;2024-01-08
2. The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export;Cell Reports;2024-01
3. DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks;Nucleic Acids Research;2023-12-01
4. Cellular Responses to Widespread DNA Replication Stress;International Journal of Molecular Sciences;2023-11-29
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