Clinical Practice Guideline by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America: 2021 Guideline on Diagnosis and Management of Acute Hematogenous Osteomyelitis in Pediatrics

Author:

Woods Charles R1,Bradley John S2,Chatterjee Archana3,Copley Lawson A4,Robinson Joan5ORCID,Kronman Matthew P6,Arrieta Antonio7,Fowler Sandra L8,Harrison Christopher9,Carrillo-Marquez Maria A10,Arnold Sandra R10,Eppes Stephen C11,Stadler Laura P12,Allen Coburn H13,Mazur Lynnette J14,Creech C Buddy15,Shah Samir S16,Zaoutis Theoklis17,Feldman David S18,Lavergne Valéry1920

Affiliation:

1. Department of Pediatrics, University of Tennessee College of Medicine, Chattanooga, Tennessee, USA

2. Division of Infectious Diseases, University of California San Diego School of Medicine, and Rady Children’s Hospital, San Diego, California, USA

3. Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, USA

4. Departments of Orthopaedic Surgery and Pediatrics, University of Texas Southwestern, Dallas, Texas, USA

5. Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada

6. Division of Infectious Diseases, Seattle Children’s Hospital, Seattle, Washington, USA

7. University of California Irvine School of Medicine and Children’s Hospital of Orange County, Irvine, California, USA

8. Division of Infectious Diseases, Medical University of South Carolina, Charleston, South Carolina, USA

9. Children Mercer Hospital, Kansas City, Missouri, USA

10. Division of Infectious Diseases, University of Tennessee Health Science Center, Memphis, Tennessee, USA

11. Department of Pediatrics, ChristianaCare, Newark, Delaware, USA

12. Department of Pediatrics, Division of Infectious Diseases, University of Kentucky, Lexington, Kentucky, USA

13. Department of Pediatrics, University of Texas at Austin Dell Medical School, Austin, Texas, USA

14. Department of Pediatrics, University of Texas McGovern Medical School, Houston, Texas, USA

15. Division of Pediatric Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

16. Division of Hospital Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

17. Division of Infectious Diseases, Children’s Hospital of Pennsylvania, Philadelphia, Pennsylvania, USA

18. New York University Langone Medical Center, New York, New York, USA

19. Department of Medical Microbiology and Infection Control, Vancouver General Hospital, Vancouver, British Columbia, Canada

20. University of Montreal Research Center, Montreal, Quebec, Canada

Abstract

Abstract This clinical practice guideline for the diagnosis and treatment of acute hematogenous osteomyelitis (AHO) in children was developed by a multidisciplinary panel representing Pediatric Infectious Diseases Society (PIDS) and the Infectious Diseases Society of America (IDSA). This guideline is intended for use by healthcare professionals who care for children with AHO, including specialists in pediatric infectious diseases, orthopedics, emergency care physicians, hospitalists, and any clinicians and healthcare providers caring for these patients. The panel’s recommendations for the diagnosis and treatment of AHO are based upon evidence derived from topic-specific systematic literature reviews. Summarized below are the recommendations for the diagnosis and treatment of AHO in children. The panel followed a systematic process used in the development of other IDSA and PIDS clinical practice guidelines, which included a standardized methodology for rating the certainty of the evidence and strength of recommendation using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. A detailed description of background, methods, evidence summary and rationale that support each recommendation, and knowledge gaps can be found online in the full text.

Funder

Infectious Diseases Society of America

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,General Medicine,Pediatrics, Perinatology, and Child Health

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