The cytogenetic constitution of human blastocysts: insights from comprehensive chromosome screening strategies

Author:

Fragouli Elpida12ORCID,Munne Santiago345,Wells Dagan12

Affiliation:

1. IVI RMA Global, Magdalen Centre Oxford Science Park, Oxford, UK

2. Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, Oxford, UK

3. Department of Obstetrics, Gynecology, and Reproductive Medicine, Yale University, New Haven, CT, USA

4. CooperGenomics, Cooper Surgical Company, 3 Regent Street, Livingston, NJ, USA

5. Overture Life, 332 Provenca 4rt, Barcelona, Spain

Funder

IVI RMA global

Oxford NIHR Biomedical Research Centre

Overture Life

Publisher

Oxford University Press (OUP)

Subject

Obstetrics and Gynecology,Reproductive Medicine

Reference64 articles.

1. The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender;Alfarawati;Fertil Steril,2011

2. Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF;Baart;Hum. Reprod,2006

3. The incidence and origin of segmental aneuploidy in human oocytes and preimplantation embryos;Babariya;Hum Reprod,2017

4. High rate of mixoploidy among human blastocysts cultured in vitro;Bielanska;Fertil Steril,2002

5. Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential;Bolton;Nat Commun,2016

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