1. Department of Life Sciences and Institute of Genome Sciences, National Yang Ming Chiao Tung University , Hsinchu , Taiwan
2. Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University , Hsinchu , Taiwan
3. Department of Geriatric Medicine, School of Medicine, National Yang Ming Chiao Tung University , Hsinchu , Taiwan
4. Department of Family Medicine, Taipei Veterans General Hospital Yuanshan Branch , Yilan , Taiwan
5. Institute of Molecular and Genomic Medicine, National Health Research Institutes , Miaoli , Taiwan
6. Center for Geriatrics and Gerontology, Taipei Veterans General Hospital , Taipei , Taiwan