Determinants of accelerated metabolomic and epigenetic aging in a UK cohort

Author:

Robinson Oliver1ORCID,Chadeau Hyam Marc1,Karaman Ibrahim1,Climaco Pinto Rui1,Ala-Korpela Mika23,Handakas Evangelos1,Fiorito Giovanni145,Gao He1,Heard Andy1,Jarvelin Marjo‐Riitta167ORCID,Lewis Matthew8,Pazoki Raha17,Polidoro Silvia15,Tzoulaki Ioanna1,Wielscher Matthias1,Elliott Paul1,Vineis Paolo15

Affiliation:

1. MRC Centre for Environment and Health Department of Epidemiology and Biostatistics School of Public Health Imperial College London London UK

2. Computational Medicine, Faculty of Medicine University of Oulu and Biocenter Oulu Oulu Finland

3. NMR Metabolomics Laboratory School of Pharmacy, University of Eastern Finland Kuopio Finland

4. Laboratory of Biostatistics Department of Biomedical Sciences University of Sassari Sassari Italy

5. Italian Institute for Genomic Medicine (IIGM, former HuGeF) Candiolo Italy

6. Center for Life Course Health Research Faculty of Medicine University of Oulu and Unit of Primary Health CareOulu University Hospital Oulu Finland

7. Department of Life Sciences College of Health and Life Sciences Brunel University London Uxbridge UK

8. National Phenome Centre Department of Metabolism Digestion and Reproduction Imperial College London London UK

Funder

Horizon 2020 Framework Programme

Publisher

Wiley

Subject

Cell Biology,Aging

Reference53 articles.

1. A metabolic view on menopause and ageing

2. Quantification of biological aging in young adults

3. Eleven telomere, epigenetic clock, and biomarker‐composite quantifications of biological aging: Do they measure the same thing?;Belsky D. W.;American Journal of Epidemiology,2017

4. Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

5. Brief screening instrument for post-traumatic stress disorder

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