Affiliation:
1. College of Science, Mustansiriyah University, Biology department.
Abstract
COVID-19 is a disease with a wide range of symptoms and severity due to the
ability of SARS-COV-2 to infect many kinds of tissues and organs in the patient's
body. The disease begins commonly with symptoms of respiratory tract infection
that may be mild and limited or progress to severe infection with fatal consequences. Vitamins play essential roles in our biology, including supporting immunity. Vitamin D deficiency became a public problem, and its effect as an immunomodulator in many viral infections was approved. This study investigated the
effect of vitamin D deficiency on cellular immunity, especially lymphocytes, in
COVID-19 patients when the disease is in its early stages. Tests were done for the
complete blood count lymphocyte proliferation assay in response to non-specific
mitogen and immunoglobulin levels. The study revealed no significant effect of
vitamin D deficiency on the T-lymphocyte activation at the early stage of the infection. Vitamin D deficient patients have lower immunoglobulin levels, necessitating vaccination against COVID-19 infection.
Keywords: COVID-19, lymphocyte proliferation, mitotic index, vitamin D
Subject
Infectious Diseases,Applied Microbiology and Biotechnology,Epidemiology,Biotechnology
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