Lineage Divergence and Vector-Specific Adaptation Have Driven Chikungunya Virus onto Multiple Adaptive Landscapes

Author:

Chen Rubing123,Plante Jessica A.1234,Plante Kenneth S.1234,Yun Ruimei123,Shinde Divya1234,Liu Jianying123,Haller Sherry123,Mukhopadhyay Suchetana5ORCID,Weaver Scott C.1234ORCID

Affiliation:

1. Institute for Human Infections and Immunology, University of Texas Medical Branch, Galveston, Texas, USA

2. Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, USA

3. Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA

4. World Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, Texas, USA

5. Department of Biology, Indiana University, Bloomington, Indiana, USA

Abstract

Since its introduction into the Caribbean in October 2013, CHIKV has rapidly spread to almost the entire neotropical region. However, its potential to further spread globally, including into more temperate climates, depends in part on its ability to be transmitted efficiently by Aedes albopictus , which can survive colder winters than A. aegypti .

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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