ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases-Reference-Cited by-同舟云学术

ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases

Published:2019-01 Issue:1 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Jacobs Michael R.¹²,Abdelhamed Ayman M.¹²,Good Caryn E.¹²,Rhoads Daniel D.¹²^ORCID,Hujer Kristine M.³⁴,Hujer Andrea M.³⁴,Domitrovic T. Nicholas³⁴,Rudin Susan D.³⁴,Richter Sandra S.⁵,van Duin David⁶^ORCID,Kreiswirth Barry N.⁷,Greco Chris⁸,Fouts Derrick E.⁸,Bonomo Robert A.³⁴⁹¹⁰¹¹

Affiliation:

1. Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA

2. Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA

3. Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA

4. Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA

5. Department of Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA

6. Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

7. Public Health Research Institute, Rutgers New Jersey Medical School, Newark, New Jersey, USA

8. J. Craig Venter Institute, Rockville, Maryland, USA

9. Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA

10. Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA

11. Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA

Abstract

The activity of the siderophore cephalosporin cefiderocol is targeted against carbapenem-resistant Gram-negative bacteria. In this study, the activity of cefiderocol against characterized carbapenem-resistant Acinetobacter baumannii complex, Stenotrophomonas maltophilia , Pseudomonas aeruginosa , and Enterobacteriaceae strains was determined by microdilution in iron-depleted Mueller-Hinton broth.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Veterans Affairs

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01801-18

Reference30 articles.

1. World Health Organization. 2017. Antibacterial agents in clinical development. An analysis of the antibacterial clinical development pipeline, including tuberculosis. Report WHO/EMP/IAU/201711. World Health Organization, Geneva, Switzerland.

2. Centers for Disease Control and Prevention. 2013. Antibiotic resistance threats in the United States 2013. Centers for Disease Control and Prevention Atlanta GA. https://www.cdc.gov/drugresistance/threat-report-2013/pdf/ar-threats-2013-508.pdf.

3. Gram-Negative Bacterial Infections: Research Priorities, Accomplishments, and Future Directions of the Antibacterial Resistance Leadership Group

4. Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae: Laboratory Detection and Impact on Mortality

5. Genome dynamics of multidrug-resistant Acinetobacter baumannii during infection and treatment

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