Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice through activation of STAT pathway-Reference-Cited by-同舟云学术

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Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice through activation of STAT pathway

Published:2017-12 Issue:1 Volume:14 Page:
ISSN:1743-8977
Container-title:Particle and Fibre Toxicology
language:en
Short-container-title:Part Fibre Toxicol

Author:

Li Xiaobo,Yang Hongbao,Wu Shenshen,Meng Qingtao,Sun Hao,Lu Runze,Cui Jian,Zheng Yuxin,Chen Wen,Zhang Rong,Aschner Michael,Chen Rui

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/content/pdf/10.1186/s12989-017-0234-0.pdf

Reference50 articles.

1. Braakhuis HM, Cassee FR, Fokkens PH, de la Fonteyne LJ, Oomen AG, Krystek P, de Jong WH, van Loveren H, Park MV. Identification of the appropriate dose metric for pulmonary inflammation of silver nanoparticles in an inhalation toxicity study. Nanotoxicology. 2016;10:63–73.

2. Ho CC, Lee HL, Chen CY, Luo YH, Tsai MH, Tsai HT, Lin P. Involvement of the cytokine-IDO1-AhR loop in zinc oxide nanoparticle-induced acute pulmonary inflammation. Nanotoxicology. 2017;11:360–70.

3. Sager TM, Wolfarth M, Leonard SS, Morris AM, Porter DW, Castranova V, Holian A. Role of engineered metal oxide nanoparticle agglomeration in reactive oxygen species generation and cathepsin B release in NLRP3 inflammasome activation and pulmonary toxicity. Inhal Toxicol. 2016;28:686–97.

4. Willhite CC, Karyakina NA, Yokel RA, Yenugadhati N, Wisniewski TM, Arnold IM, Momoli F, Krewski D. Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts. Crit Rev Toxicol. 2014;44(Suppl 4):1–80.

5. Chen L, Yokel RA, Hennig B, Toborek M. Manufactured aluminum oxide nanoparticles decrease expression of tight junction proteins in brain vasculature. J NeuroImmune Pharmacol. 2008;3:286–95.

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