Exfoliated epithelial cell transcriptome reflects both small and large intestinal cell signatures in piglets

Author:

Yoon Grace1,Davidson Laurie A.23,Goldsby Jennifer S.23,Mullens Destiny A.34,Ivanov Ivan4,Donovan Sharon M.5,Chapkin Robert S.23

Affiliation:

1. Department of Statistics, Texas A&M University, College Station, Texas

2. Department of Nutrition, Texas A&M University, College Station Texas

3. Program in Integrative Nutrition & Complex Diseases, Texas A&M University, College Station, Texas

4. Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas

5. Department of Food Science and Human Nutrition, University of Illinois, Urbana-Champaign, Illinois

Abstract

The transcriptome of exfoliated epithelial cells in stool contain gene signatures from both small and large intestinal mucosa affording a noninvasive approach to assess gut health and function.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Physiological Society

Subject

Physiology (medical),Gastroenterology,Hepatology,Physiology

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