Microsatellite Instability Phenotype of Tumors: Genotyping or Immunohistochemistry? The Jury Is Still Out

Author:

de la Chapelle Albert1

Affiliation:

1. Ohio State University, Columbus, OH

Publisher

American Society of Clinical Oncology (ASCO)

Subject

Cancer Research,Oncology

Reference16 articles.

1. Genetic instabilities in human cancers

2. Boland CR, Thibodeau SN, Hamilton SR, et al: A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248,1998-5257,

3. Clues to the Pathogenesis of Familial Colorectal Cancer

4. Kane MF, Loda M, Gaida GM, et al: Methylation of the promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 57: 4749,1997-4756, hMLH1

5. Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors

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