<i>In vitro</i> and <i>In silico</i> anticancer activities of Mn(<scp>ii</scp>), Co(<scp>ii</scp>), and Ni(<scp>ii</scp>) complexes: synthesis, characterization, crystal structures, and DFT studies-Reference-Cited by-同舟云学术

In vitro and In silico anticancer activities of Mn(ii), Co(ii), and Ni(ii) complexes: synthesis, characterization, crystal structures, and DFT studies

Published:2022 Issue:23 Volume:46 Page:11056-11070
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Gond M. K.¹,Pandey Shivendra Kumar¹^ORCID,Singh R.²,Bharty Manoj K.¹^ORCID,Manna Partha Pratim²^ORCID,Singh V. K.³,Maiti B.¹^ORCID,Prasad L. B.¹,Butcher R. J.⁴^ORCID

Affiliation:

1. Department of Chemistry, Banaras Hindu University, Varanasi-221005, India

2. Department of Zoology Banaras Hindu University, Varanasi-221005, India

3. School of Biotechnology, Banaras Hindu University, Varanasi-221005, India

4. Department of Chemistry, Howard University, 525 College Street NW, Washington, DC 20059, USA

Abstract

Complexes 1, 2 and 3 showed significant activity against K562, MCF-7, and DL cancer cell lines. Complexes 1–3 showed higher growth inhibition than metal salts or ligands in tumour cell growth and colony formation. Complex 1 exhibited higher anticancer activity than cisplatin.

Funder

Banaras Hindu University

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ00264G

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