A DNA tetrahedron-loaded natural photosensitizer with aggregation-induced emission characteristics for boosting fluorescence imaging-guided photodynamic therapy-Reference-Cited by-同舟云学术

A DNA tetrahedron-loaded natural photosensitizer with aggregation-induced emission characteristics for boosting fluorescence imaging-guided photodynamic therapy

Published:2021 Issue:14 Volume:5 Page:5410-5417
ISSN:2052-1537
Container-title:Materials Chemistry Frontiers
language:en
Short-container-title:Mater. Chem. Front.

Author:

Zhu Wei¹²³⁴⁵^ORCID,Ma Ke¹²³⁴⁵,Yan Zhi-Chao¹²³⁴⁵^ORCID,Wu Qian¹²³⁴⁵,Wang Dong¹²³⁴⁵^ORCID,Tang Ben Zhong⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Shenzhen Key Laboratory of Polymer Science and Technology

2. Guangdong Research Center for Interfacial Engineering of Functional Material

3. College of Materials Science and Engineering

4. Shenzhen University

5. Shenzhen 518060

6. Department of Chemistry

7. Hong Kong Branch of Chinese National Engineering Research

8. Center for Tissue Restoration and Reconstruction

9. Hong KongUniversity of Science and Technology

10. Kowloon

Abstract

A natural AIE-active PS (PaH) is utilized to bind into DNA-T for cancer theranostics. The constructed PaH@DNA-T exhibits highly boosted fluorescence intensity and ROS generation, as well as much higher cell uptake efficiency.

Funder

National Natural Science Foundation of China

Shenzhen Science and Technology Innovation Commission

Natural Science Foundation of Guangdong Province for Distinguished Young Scholars

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QM/D1QM00420D

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1. Cancer statistics, 2020