Immunostimulatory silica nanoparticle boosts innate immunity in brain tumors

Author:

Bielecki Peter A.12345,Lorkowski Morgan E.12345,Becicka Wyatt M.1234,Atukorale Prabhani U.12345,Moon Taylor J.1234,Zhang Yahan1234,Wiese Michelle1234,Covarrubias Gil12345,Ravichandran Shruthi674,Karathanasis Efstathios12345ORCID

Affiliation:

1. Department of Biomedical Engineering

2. Case Western Reserve University

3. Cleveland

4. USA

5. Case Comprehensive Cancer Center

6. Hathaway Brown School

7. Shaker Heights

Abstract

An immunostimulatory nanoparticle was specifically designed to boost the local innate immune compartment of brain tumors leading to a robust antitumor immune response.

Funder

National Center for Advancing Translational Sciences

Alex's Lemonade Stand Foundation for Childhood Cancer

National Institute of Biomedical Imaging and Bioengineering

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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