Novel asymmetrical azines appending 1,3,4-thiadiazole sulfonamide: synthesis, molecular structure analyses, <i>in silico</i> ADME, and cytotoxic effect-Reference-Cited by-同舟云学术

Novel asymmetrical azines appending 1,3,4-thiadiazole sulfonamide: synthesis, molecular structure analyses, in silico ADME, and cytotoxic effect

Published:2023 Issue:15 Volume:13 Page:10353-10366
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Bondock Samir¹²^ORCID,Albarqi Tallah¹,Shaaban Ibrahim A.¹³,Abdou Moaz M.⁴^ORCID

Affiliation:

1. Chemistry Department, Faculty of Science, King Khalid University, 9004 Abha, Saudi Arabia

2. Chemistry Department, Faculty of Science, Mansoura University, 35516 Mansoura, Egypt

3. Department of Chemistry, Faculty of Science (Men's Campus), Al-Azhar University, Nasr City 11884, Cairo, Egypt

4. Egyptian Petroleum Research Institute, Nasr City, 11727, Cairo, Egypt

Abstract

Toward finding potential and novel anticancer agents, we designed and prepared novel differently substituted unsymmetrical azine-modified thiadiazole sulfonamide derivatives using the “combi-targeting approach”.

Funder

King Khalid University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA00123G

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