A selective fluorescent sensor for cysteine detection with potential as a white light emitting fluorophore in living cell imaging

Author:

Yang Yu-Shun12345,Yuan Zeng-Hui12345,Zhang Xu-Ping12345,Xu Jian-Fei12345,Lv Peng-Cheng12345,Zhu Hai-Liang12345ORCID

Affiliation:

1. State Key Laboratory of Pharmaceutical Biotechnology

2. School of Life Sciences

3. Nanjing University

4. Nanjing

5. China

Abstract

A novel fluorescent sensor CysW-1 was introduced for cysteine detection via the cleavage reaction of two fluorophores. Then a relatively steady and practical white light emitting system was successfully generated. The biocompatibility ensured the living cell imaging and further pre-clinical applications.

Funder

National Natural Science Foundation of China

Major Science and Technology Program for Water Pollution Control and Treatment

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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