Galactosylated biodegradable poly(ε-caprolactone-co-phosphoester) random copolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin-Reference-Cited by-同舟云学术

Galactosylated biodegradable poly(ε-caprolactone-co-phosphoester) random copolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin

Published:2014 Issue:10 Volume:5 Page:3443-3452
ISSN:1759-9954
Container-title:Polym. Chem.
language:en
Short-container-title:Polym. Chem.

Author:

Tao Yunfeng¹²³⁴⁵,He Jinlin¹²³⁴⁵,Zhang Mingzu¹²³⁴⁵,Hao Ying¹²³⁴⁵,Liu Jian⁶⁷⁴⁸,Ni Peihong¹²³⁴⁵

Affiliation:

1. College of Chemistry

2. Chemical Engineering and Materials Science

3. Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application

4. Soochow University

5. Suzhou 215123, P. R. China

6. Institute of Functional Nano & Soft Materials (FUNSOM)

7. Collaborative Innovation Center of Suzhou Nano Science and Technology

8. Suzhou, P. R. China

Abstract

A novel biocompatible and biodegradable poly(ε-caprolactone-co-phosphoester) random copolymer conjugated with galactosamine has been synthesized and used for hepatoma-targeting delivery of doxorubicin.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2014/PY/C4PY00024B

Reference49 articles.

1. Polymer conjugates as anticancer nanomedicines

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3. Drug Delivery Systems: Entering the Mainstream

4. Polymeric Systems for Controlled Drug Release

5. Block copolymer micelles for drug delivery: design, characterization and biological significance

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