A reduced polydopamine nanoparticle-coupled sprayable PEG hydrogel adhesive with anti-infection activity for rapid wound sealing

Author:

Sun Junjie12345,Tan Haoqi12345ORCID,Liu Huan12345,Jin Dawei678910,Yin Meng678910,Lin Haodong1112131014,Qu Xue12345ORCID,Liu Changsheng12345ORCID

Affiliation:

1. Key Laboratory for Ultrafine Materials of Ministry of Education

2. Frontiers Science Center for Materiobiology and Dynamic Chemistry

3. School of material science and engineering

4. East China University of Science and Technology

5. Shanghai 200237

6. Department of Cardiothoracic Surgery

7. Shanghai Children's Medical Center

8. School of Medicine

9. Shanghai Jiao Tong University

10. Shanghai

11. Department of Orthopedic Surgery

12. Shanghai General Hospital

13. Shanghai Jiaotong University School of Medicine

14. China

Abstract

A novel sprayable PEG-PDA hydrogel adhesive can instantly gel to close wounds, providing synergistic antibacterial activities through ROS and hyperthermia.

Funder

National Natural Science Foundation of China

Science and Technology Commission of Shanghai Municipality

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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