B(C6F5)3-catalyzed β-C(sp3)–H alkylation of tertiary amines with 2-aryl-3H-indol-3-ones-Reference-Cited by-同舟云学术

B(C₆F₅)₃-catalyzed β-C(sp³)–H alkylation of tertiary amines with 2-aryl-3H-indol-3-ones

Published:2023 Issue:21 Volume:21 Page:4393-4397
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zou Chang-Peng¹,Ma Tao¹,Qiao Xiu-Xiu¹,Wu Xi-Xi¹,Li Ganpeng¹,He Yonghui¹^ORCID,Zhao Xiao-Jing¹^ORCID

Affiliation:

1. Key Laboratory of Chemistry in Ethnic Medicinal Resources, Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal Endophytes, State Ethnic Affairs Commission & Ministry of Education, School of Ethnic Medicine, Yunnan Minzu University, Kunming, 650500, China

Abstract

Herein, we describe a B(C6F5)3-catalyzed redox-neutral β-functionalization of tertiary amines with cyclic-ketimines, achieving various 1,3-diamines containing the indolin-3-one moietyviathe borrowing hydrogen strategy.

Funder

National Natural Science Foundation of China

Minzu University of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00481C

Reference97 articles.

1. History, chemistry and biology of alkaloids from Lobelia inflata

2. Direct sp3C–H bond activation adjacent to nitrogen in heterocycles