Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility-Reference-Cited by-同舟云学术

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility

Published:2011-08-16 Issue:10 Volume:2 Page:747-751
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Jia Lanqi¹,Simpson Robert D.¹,Yuan Jing¹,Xu Zhenrong¹,Zhao Wei¹,Cacatian Salvacion¹,Tice Colin M.¹,Guo Joan¹,Ishchenko Alexey¹,Singh Suresh B.¹,Wu Zhongren¹,McKeever Brian M.¹,Bukhtiyarov Yuri¹,Johnson Judith A.¹,Doe Christopher P.²,Harrison Richard K.¹,McGeehan Gerard M.¹,Dillard Lawrence W.¹,Baldwin John J.¹,Claremon David A.¹

Affiliation:

1. Vitae Pharmaceuticals, 502 West Office Center Drive, Fort Washington, Pennsylvania 19034, United States

2. GlaxoSmithKline, 709 Swedeland Road, King of Prussia, Pennsylvania 19406, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml200137x

Reference26 articles.

1. THE PREPARATION, PURIFICATION, AND AMINO ACID SEQUENCE OF A POLYPEPTIDE RENIN SUBSTRATE

2. The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease

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4. Update on tissue renin–angiotensin systems

5. Drugs targeting the renin–angiotensin–aldosterone system

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