pH/hypoxia programmable triggered cancer photo-chemotherapy based on a semiconducting polymer dot hybridized mesoporous silica framework

Author:

Zhang Da12345ORCID,Cai Zhixiong678910,Liao Naishun6789,Lan Shanyou6789,Wu Ming6789ORCID,Sun Haiyan111213149,Wei Zuwu6789ORCID,Li Juan12345,Liu Xiaolong6789ORCID

Affiliation:

1. MOE Key Laboratory for Analytical Science of Food Safety and Biology

2. State Key Laboratory of Photocatalysis on Energy and Environment

3. College of Chemistry

4. Fuzhou University

5. Fuzhou 350116

6. The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province

7. Mengchao Hepatobiliary Hospital of Fujian Medical University

8. Fuzhou 350025

9. P. R. China

10. Key Laboratory of Biomedical Information Engineering of Ministry of Education

11. Department of Anesthesiology

12. Beijing Anzhen Hospital

13. Capital Medical University

14. Beijing 100029

Abstract

We have integrated the pH/hypoxia-triggered Fe(iii)-banoxantrone (AQ4N) prodrug and semiconducting polymer dots (SPs) for programmable triggered cancer photothermal-chemotherapy.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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