Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums
Author:
Affiliation:
1. Key Laboratory of Receptor Research
2. Drug Discovery and Design Center
3. Shanghai Institute of Materia Medica
4. Chinese Academy of Sciences
5. Shanghai 201203
Abstract
A new metal-free method for theN-quinolylation of primary amino groups using novel dihydrooxazolo[3,2-a]quinoliniums showing good compatibility with other reactive moieties.
Funder
National Basic Research Program of China
National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Pollution,Environmental Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/GC/C9GC01442J
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1. Peptide therapeutics: current status and future directions
2. The Future of Peptide-based Drugs
3. Studying protein–protein interactions using peptide arrays
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1. Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium;Journal of Medicinal Chemistry;2022-08-22
2. Amino-based covalent organic frameworks for a wide range of functional modification;New Journal of Chemistry;2022
3. An aza-Diels–Alder route to quinoline-based unnatural amino acids and polypeptide surrogates;RSC Advances;2021
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