Nano–bio interaction between human immunoglobulin G and nontoxic, near-infrared emitting water-borne silicon quantum dot micelles

Author:

Chinnathambi Shanmugavel12ORCID,Shirahata Naoto345ORCID,Kumar Mahima1,Karthikeyan Subramani6,Abe Katsuhiko1,Thangavel Vaijayanthi1,Pandian Ganesh N.1

Affiliation:

1. Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Institute for Advanced Study, Kyoto University, Kyoto 606-8501, Japan

2. International Center for Young Scientists, National Institute for Materials Science (NIMS), 1-2-1 Sengen, Tsukuba 305-0047, Ibaraki, Japan

3. Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0814, Japan

4. International Center for Materials Nanoarchitectonics (WPI-MANA), NIMS, Namiki, Tsukuba 305-0044, Japan

5. Department of Physics, Chuo University, 1-13-27 Kasuga, Bunkyo, Tokyo 112-8551, Japan

6. Centre for Healthcare Advancement, Innovation and Research, Vellore Institute of Technology, Chennai, 600 127, India

Abstract

We prepared Pluronic-F127 coated silicon quantum dot micelles and examined their interaction with Human IgG. Furthermore, the micelles were used to image cells as well as medaka (Oryzias latipes) eggs and larvae without causing cytotoxicity.

Funder

Japan Society for the Promotion of Science

Uehara Memorial Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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