Solid phase extraction procedure coupled with the chiral LC-ESI-MS/MS method for the enantioseparation and determination of butoconazole enantiomers in rat plasma and tissues: application to the enantioselective study on pharmacokinetics and tissue distribution-Reference-Cited by-同舟云学术

Solid phase extraction procedure coupled with the chiral LC-ESI-MS/MS method for the enantioseparation and determination of butoconazole enantiomers in rat plasma and tissues: application to the enantioselective study on pharmacokinetics and tissue distribution

Published:2021 Issue:3 Volume:45 Page:1317-1326
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Ma Siman¹²³,Wang Lina⁴⁵⁶,Guo Guoxian⁴⁵⁶,Yu Jia¹²³^ORCID,Guo Xingjie¹²³^ORCID

Affiliation:

1. Lab of analytical chemistry, School of Pharmacy, Shenyang Pharmaceutical University

2. Shenyang

3. P. R. China

4. Department of Animal products and Fishery products, Liaoning Institute for Agro-product Veterinary Drugs and Feed Control, Liaoning Inspection, Examination & Certification Center

5. Shenyang 110000

6. China

Abstract

A significant enantioselective difference between (−)- and (+)-butoconazole existed in the stage of not only pharmacokinetics but also tissue distribution.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D0NJ04760K

Reference16 articles.

1. Enantiospecific determination of arotinolol in rat plasma by LC–MS/MS: Application to a stereoselective pharmacokinetic study

2. Chiral liquid chromatography–mass spectrometry (LC–MS/MS) method development for the detection of salbutamol in urine samples

3. Development of a liquid chromatography-tandem mass spectrometry method for determination of butoconazole nitrate in human plasma and its application to a pharmacokinetic study

4. Butoconazole nitrate pharmacokinetics studied by capillary electrophoresis

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