The enantioseparation and determination of sulconazole enantiomers in rat plasma and tissues by a chiral HPLC–ESI–MS/MS method and its application to studies on stereoselective pharmacokinetics and tissue distribution-Reference-Cited by-同舟云学术

The enantioseparation and determination of sulconazole enantiomers in rat plasma and tissues by a chiral HPLC–ESI–MS/MS method and its application to studies on stereoselective pharmacokinetics and tissue distribution

Published:2022 Issue:9 Volume:46 Page:4262-4271
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Ma Siman¹,Wang Lina²,Guo Guoxian²,Tang Jing³,Yu Jia¹^ORCID

Affiliation:

1. Lab of Aalytical Chemistry, School of Pharmacy, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenyang 110016, China

2. Department of Animal products and Fishery products, Liaoning Institute for Agro-product Veterinary Drugs and Feed Control, Liaoning Inspection, Examination & Certification Center, Shenyang 110000, China

3. Department of Pharmacy, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China

Abstract

In our study, a chiral high performance liquid chromatography–electrospray ionization coupled with tandem mass spectrometry (HPLC–ESI–MS/MS) method for enantioselective analysis of sulconazole in rat plasma and tissues was developed and validated.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D1NJ04882A

Reference21 articles.

1. Enantioselective analysis of lansoprazole in rat plasma by LC-MS/MS: Application to a stereoselective pharmacokinetic study

2. Enantioseparation and determination of alminoprofen in rat plasma and its application to a stereoselective pharmacokinetic study

3. Enantiospecific determination of arotinolol in rat plasma by LC–MS/MS: Application to a stereoselective pharmacokinetic study

4. Chiral liquid chromatography–mass spectrometry (LC–MS/MS) method development for the detection of salbutamol in urine samples

5. Structural confirmation of sulconazole sulfoxide as the primary degradation product of sulconazole nitrate

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enantioselective evaluation of chiral cosmetic preservative chlorphenesin on cytotoxicity, pharmacokinetics and tissue distribution;Microchemical Journal;2023-04

2. Study of Different Chiral Columns for the Enantiomeric Separation of Azoles Using Supercritical Fluid Chromatography;Separations;2022-12-23