NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel

Author:

Hamaguchi T,Matsumura Y,Suzuki M,Shimizu K,Goda R,Nakamura I,Nakatomi I,Yokoyama M,Kataoka K,Kakizoe T

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference22 articles.

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2. Hamaguchi T, Matsumura Y, Shirao Y, Shimada Y, Yamada Y, Muro Y, Okusaka T, Ueno H, Ikeda M, Watanabe N (2003) Phase I study of novel drug delivery system, NK911, a polymer micelle encapsulated doxorubicin. Proc Am Soc Clin Oncol 22: 571

3. Ibrahim NK, Desai N, Legha S, Soon-Shiong P, Theriault RL, Rivera E, Esmaeli B, Ring SE, Bedikian A, Hortobagyi GN, Ellerhorst JA (2002) Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. Clin Cancer Res 8: 1038–1044

4. Jain RK (1994) Barriers to drug delivery in solid tumours. Sci Am 271: 58–65

5. Kataoka K, Kwon GS, Yokoyama M, Okano T, Sakurai Y (1993) Block copolymer micelles as vehicles for drug delivery. J Control Rel 24: 119–132

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