The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain-Reference-Cited by-同舟云学术

The M1/M4 preferring muscarinic agonist xanomeline modulates functional connectivity and NMDAR antagonist-induced changes in the mouse brain

Published:2020-12-20 Issue:6 Volume:46 Page:1194-1206
ISSN:0893-133X
Container-title:Neuropsychopharmacology
language:en
Short-container-title:Neuropsychopharmacol.

Author:

Montani Caterina^ORCID,Canella Carola,Schwarz Adam J.,Li Jennifer,Gilmour Gary,Galbusera Alberto^ORCID,Wafford Keith,Gutierrez-Barragan Daniel,McCarthy Andrew,Shaw David,Knitowski Karen,McKinzie David,Gozzi Alessandro,Felder Christian

Publisher

Springer Science and Business Media LLC

Subject

Psychiatry and Mental health,Pharmacology

Link

http://www.nature.com/articles/s41386-020-00916-0.pdf

Reference95 articles.

1. Shannon HE, Rasmussen K, Bymaster FP, Hart JC, Peters SC, Swedberg MDB, et al. Xanomeline, an M1/M4 preferring muscarinic cholinergic receptor agonist, produces antipsychotic-like activity in rats and mice. Schizophr Res. 2000;42:249–59. https://doi.org/10.1016/S0920-9964(99)00138-3

2. Andersen MB, Fink-Jensen A, Peacock L, Gerlach J, Bymaster F, Lundbaek JA, et al. The muscarinic M1/M4 receptor agonist xanomeline exhibits antipsychotic-like activity in Cebus apella monkeys. Neuropsychopharmacology. 2003;28:1168–75. https://doi.org/10.1038/sj.npp.1300151

3. Mirza NR, Peters D, Sparks RG. Xanomeline and the antipsychotic potential of muscarinic receptor subtype selective agonists. CNS Drug Rev. 2003;9:159–86. https://doi.org/10.1111/j.1527-3458.2003.tb00247.x

4. Martino G, Puma C, Yu XH, Gilbert AK, Coupal M, Markoglou N, et al. The M1/M4 preferring agonist xanomeline is analgesic in rodent models of chronic inflammatory and neuropathic pain via central site of action. Pain. 2011;152:2852–60. https://doi.org/10.1016/j.pain.2011.09.017

5. Thorn CA, Moon J, Bourbonais CA, Harms J, Edgerton JR, Stark E, et al. Striatal, HIppocampal, And Cortical Networks Are Differentially Responsive to the M4- and M1-muscarinic acetylcholine receptor mediated effects of xanomeline. ACS Chem Neurosci. 2019;10:1753–64. https://doi.org/10.1021/acschemneuro.8b00625

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Efficacy of KarXT on negative symptoms in acute schizophrenia: A post hoc analysis of pooled data from 3 trials;Schizophrenia Research;2024-12

2. Long-term adaptation of prefrontal circuits in a mouse model of NMDAR hypofunction;Neuropharmacology;2024-08

3. Clinical utility of fMRI in evaluating of LSD effect on pain-related brain networks in healthy subjects;Heliyon;2024-08

4. Sex-biasing influence of autism-associated Ube3a gene overdosage at connectomic, behavioral, and transcriptomic levels;Science Advances;2024-07-12

5. Neurochemical organization of cortical proteinopathy and neurophysiology along the Alzheimer's disease continuum;Alzheimer's & Dementia;2024-07-12