Striatal, Hippocampal, and Cortical Networks Are Differentially Responsive to the M4- and M1-Muscarinic Acetylcholine Receptor Mediated Effects of Xanomeline
Author:
Affiliation:
1. Primary Pharmacology Group, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States
Publisher
American Chemical Society (ACS)
Subject
Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00625
Reference54 articles.
1. Cholinergic contributions to the cognitive symptoms of schizophrenia and the viability of cholinergic treatments
2. Cognitive deficits in schizophrenia: an updated metanalysis of the scientific evidence
3. Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia
4. Psychosis in Alzheimer’s Disease
5. Utility of extrapyramidal signs and psychosis as predictors of cognitive and functional decline, nursing home admission, and death in Alzheimer's disease: Prospective analyses from the Predictors Study
Cited by 21 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Current Findings and Potential Mechanisms of KarXT (Xanomeline–Trospium) in Schizophrenia Treatment;Clinical Drug Investigation;2024-06-21
2. Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M4 Muscarinic Acetylcholine Receptor;Journal of Medicinal Chemistry;2024-06-18
3. Beyond dopamine: Novel strategies for schizophrenia treatment;Medicinal Research Reviews;2024-04-23
4. Understanding the Therapeutic Action of Antipsychotics: From Molecular to Cellular Targets With Focus on the Islands of Calleja;International Journal of Neuropsychopharmacology;2024-04-01
5. Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR;Nature Communications;2023-09-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3