Viral and cellular RNA helicases as antiviral targets
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd1853.pdf
Reference90 articles.
1. De Clercq, E. Antivirals and antiviral strategies. Nature Rev. Microbiol. 2, 704–720 (2004).
2. De Clercq, E. Strategies in the design of antiviral drugs. Nature Rev. Drug Discov. 1, 13–25 (2002). References 1 and 2 are good overviews of antiviral drug discovery strategies.
3. Richman, D. D. The implications of drug resistance for strategies of combination antiviral chemotherapy. Antiviral Res. 29, 31–33 (1996).
4. Lohman, T. M. & Bjornson, K. P. Mechanisms of helicase-catalyzed DNA unwinding. Annu. Rev. Biochem. 65, 169–214 (1996). Provides a detailed review of helicase mechanism.
5. Soultanas, P. & Wigley, D. B. Unwinding the 'Gordian knot' of helicase action. Trends Biochem. Sci. 26, 47–54 (2001). A short, but very insightful, review of helicase mechanism of action.
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