Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate-Reference-Cited by-同舟云学术

Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate

Published:2019-11-11 Issue:23 Volume:62 Page:10563-10582
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ramdas Vidya¹^ORCID,Talwar Rashmi¹,Banerjee Moloy¹,Joshi Advait Arun¹,Das Amit Kumar¹,Walke Deepak Sahebrao¹,Borhade Prashant¹,Dhayagude Usha¹,Loriya Rajesh¹,Gote Ganesh¹,Bommakanti Apparao¹,Sivaram Aruna¹,Agarwal Gautam¹,Goswami Arnab¹,Nigade Prashant¹,Mehta Maneesh¹,Patil Vinod¹,Modi Dipak¹,Kumar Hemant¹,Mallurwar Sadanand¹,Dash Amruta¹,Modi Falguni¹,Kuldharan Sandip¹,Srivastava Pratima¹,Singh Minakshi¹,Narasimham Lakshmi¹,Gundu Jayasagar¹,Sharma Sharad¹,Kamboj Rajender Kumar¹,Palle Venkata P.¹

Affiliation:

1. Novel Drug Discovery & Development, Lupin Ltd., Lupin Research Park, Survey No. 46 A/47 A, Village Nande, Taluka Mulshi, Pune 412115, India

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01562

Reference42 articles.

1. https://www.who.int/en/news-room/fact-sheets/detail/hepatitis-c (accessed May 6, 2019).

2. Hepatitis C virus: Morphogenesis, infection and therapy

3. Global distribution and prevalence of hepatitis C virus genotypes

4. Introduction to hepatitis C virus infection: Overview and history of hepatitis C virus therapies

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