Identification of Novel Cyclooxygenase-2 Selective Inhibitors Using Pharmacophore Models-Reference-Cited by-同舟云学术

Identification of Novel Cyclooxygenase-2 Selective Inhibitors Using Pharmacophore Models

Published:2002-02-26 Issue:7 Volume:45 Page:1402-1411
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Palomer Albert¹,Cabré Francesc¹,Pascual Jaume¹,Campos Joaquín¹,Trujillo María A.¹,Entrena Antonio¹,Gallo Miguel A.¹,García Lluïsa¹,Mauleón David¹,Espinosa Antonio¹

Affiliation:

1. R&D Department, Laboratorios Menarini S.A., Alfonso XII 587, 08918 Badalona, Spain, and Departamento de Química Orgánica, Facultad de Farmacia, Universidad de Granada, Campus de la Cartuja s/n, 18071 Granada, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm010458r

Reference32 articles.

1. Inhibition of Prostaglandin Synthetase in Brain explains the Anti-pyretic Activity of Paracetamol (4-Acetamidophenol)

2. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.

3. Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

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