Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor-Reference-Cited by-同舟云学术

Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor

Published:2010-08-04 Issue:17 Volume:53 Page:6368-6377
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cee Victor J.¹,Schenkel Laurie B.¹,Hodous Brian L.¹,Deak Holly L.¹,Nguyen Hanh N.¹,Olivieri Philip R.¹,Romero Karina¹,Bak Annette²,Be Xuhai³,Bellon Steve⁴,Bush Tammy L.⁵,Cheng Alan C.⁴,Chung Grace⁵,Coats Steve⁵,Eden Patrick M.⁵,Hanestad Kelly⁵,Gallant Paul L.⁶,Gu Yan⁴,Huang Xin⁴,Kendall Richard L.⁵,Lin Min-Hwa Jasmine³,Morrison Michael J.⁶,Patel Vinod F.¹,Radinsky Robert⁵,Rose Paul E.⁴,Ross Sandra⁶,Sun Ji-Rong⁵,Tang Jin⁴,Zhao Huilin⁴,Payton Marc⁵,Geuns-Meyer Stephanie D.¹

Affiliation:

1. Medicinal Chemistry

2. Pharmaceutics

3. Pharmacokinetics and Drug Metabolism

4. Molecular Structure

5. Oncology Research

6. Molecular Pharmacology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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