The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review

Author:

Xie Zhiyi123,Jiang Ninghua4,Lin Minqiu23,He Xinglishang23,Li Bo23,Dong Yingjie123,Chen Suhong123,Lv Guiyuan1

Affiliation:

1. College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China

2. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Huzhou 313200, China

3. Zhejiang Provincial Key Laboratory of TCM for Innovative R & D and Digital Intelligent Manufacturing of TCM Great Health Products, Huzhou 313200, China

4. The Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, China

Abstract

Tonic Chinese herbal medicine is a type of traditional Chinese medicine, and its primary function is to restore the body’s lost nutrients, improve activity levels, increase disease resistance, and alleviate physical exhaustion. The body’s immunity can be strengthened by its polysaccharide components, which also have a potent immune-system-protecting effect. Several studies have demonstrated that tonic Chinese herbal medicine polysaccharides can improve the body’s immune response to tumor cells, viruses, bacteria, and other harmful substances. However, the regulatory mechanisms by which various polysaccharides used in tonic Chinese herbal medicine enhance immune function vary. This study examines the regulatory effects of different tonic Chinese herbal medicine polysaccharides on immune organs, immune cells, and immune-related cytokines. It explores the immune response mechanism to understand the similarities and differences in the effects of tonic Chinese herbal medicine polysaccharides on immune function and to lay the foundation for the future development of tonic Chinese herbal medicine polysaccharide products.

Funder

National Natural Science Foundation of China

Key R&D Program of Zhejiang Province

Jiaxing Science and Technology Plan Project

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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