Influence of the Mediterranean Diet on Healthy Aging

Author:

Andreo-López Maria Carmen1,Contreras-Bolívar Victoria12,Muñoz-Torres Manuel1234ORCID,García-Fontana Beatriz235ORCID,García-Fontana Cristina123ORCID

Affiliation:

1. Endocrinology and Nutrition Unit, University Hospital Clínico San Cecilio, 18016 Granada, Spain

2. Instituto de Investigación Biosanitaria de Granada (Ibs. Granada), 18014 Granada, Spain

3. CIBER on Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, 18012 Granada, Spain

4. Department of Medicine, University of Granada, 18016 Granada, Spain

5. Department of Cell Biology, University of Granada, 18016 Granada, Spain

Abstract

The life expectancy of the global population has increased. Aging is a natural physiological process that poses major challenges in an increasingly long-lived and frail population. Several molecular mechanisms are involved in aging. Likewise, the gut microbiota, which is influenced by environmental factors such as diet, plays a crucial role in the modulation of these mechanisms. The Mediterranean diet, as well as the components present in it, offer some proof of this. Achieving healthy aging should be focused on the promotion of healthy lifestyle habits that reduce the development of pathologies that are associated with aging, in order to increase the quality of life of the aging population. In this review we analyze the influence of the Mediterranean diet on the molecular pathways and the microbiota associated with more favorable aging patterns, as well as its possible role as an anti-aging treatment.

Funder

Junta de Andalucia

Instituto de Salud Carlos III

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Reference377 articles.

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