Mediterranean Diet and Ultra-Processed Food Intake in Older Australian Adults—Associations with Frailty and Cardiometabolic Conditions

Author:

Clayton-Chubb Daniel1234ORCID,Vaughan Nicole V.5,George Elena S.6ORCID,Chan Andrew T.789,Roberts Stuart K.12ORCID,Ryan Joanne10ORCID,Phyo Aung Zaw Zaw10,McNeil John J.10ORCID,Beilin Lawrence J.11ORCID,Tran Cammie10,Wang Yiqing789ORCID,Sevilla-Gonzalez Magdalena7912ORCID,Wang Dong D.1314,Kemp William W.12ORCID,Majeed Ammar12,Woods Robyn L.10ORCID,Owen Alice J.10ORCID,Fitzpatrick Jessica A.12ORCID

Affiliation:

1. Department of Gastroenterology, Alfred Health, 99 Commercial Rd, Melbourne 3004, Australia

2. School of Translational Medicine, Monash University, Melbourne 3004, Australia

3. Department of Gastroenterology, Eastern Health, Box Hill 3128, Australia

4. Department of Gastroenterology, St. Vincent’s Hospital Melbourne, Fitzroy 3065, Australia

5. Department of Nutrition & Dietetics, Alfred Health, Melbourne 3004, Australia

6. Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong 3220, Australia

7. Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA 02114, USA

8. Division of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114, USA

9. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA

10. School of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia

11. Medical School, Royal Perth Hospital, University of Western Australia, Perth 6000, Australia

12. Programs in Metabolism and Medical & Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA

13. Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA

14. Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA

Abstract

Dietary patterns contribute to overall health and diseases of ageing but are understudied in older adults. As such, we first aimed to develop dietary indices to quantify Mediterranean Diet Score (MDS) utilisation and Ultra-processed Food (UPF) intake in a well-characterised cohort of relatively healthy community-dwelling older Australian adults. Second, we aimed to understand the relationship between these scores and the association of these scores with prevalent cardiometabolic disease and frailty. Our major findings are that in this population of older adults, (a) pre-frailty and frailty are associated with reduced MDS and increased UPF intake; (b) adherence to MDS eating patterns does not preclude relatively high intake of UPF (and vice versa); and (c) high utilisation of an MDS eating pattern does not prevent an increased risk of frailty with higher UPF intakes. As such, the Mediterranean Diet pattern should be encouraged in older adults to potentially reduce the risk of frailty, while the impact of UPF intake should be further explored given the convenience these foods provide to a population whose access to unprocessed food may be limited due to socioeconomic, health, and lifestyle factors.

Funder

National Institute on Aging

NHMRC

Monash University

Victorian Cancer Agency

ANZ Trustees

Wicking Trust

Mason Foundation

Australian RTP Scholarship

Crohn’s and Colitis Australia PhD scholarship

American Diabetes Association

Publisher

MDPI AG

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