Abstract
One of the most widely distributed soft coral species, found especially in shallow waters of the Indo-Pacific region, Red Sea, Mediterranean Sea, and also the Arctic, is genus Sacrophyton. The total number of species belonging to it was estimated to be 40. Sarcophyton species are considered to be a reservoir of bioactive natural metabolites. Secondary metabolites isolated from members belonging to this genus show great chemical diversity. They are rich in terpenoids, in particular, cembranoids diterpenes, tetratepenoids, triterpenoids, and ceramide, in addition to steroids, sesquiterpenes, and fatty acids. They showed a broad range of potent biological activities, such as antitumor, neuroprotective, antimicrobial, antiviral, antidiabetic, antifouling, and anti-inflammatory activity. This review presents all isolated secondary metabolites from species of genera Sacrophyton, as well as their reported biological activities covering a period of about two decades (1998–2019). It deals with 481 metabolites, including 323 diterpenes, 39 biscembranoids, 11 sesquiterpenes, 53 polyoxygenated sterols, and 55 miscellaneous and their pharmacological activities.
Subject
Drug Discovery,Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science
Reference136 articles.
1. The Function of Surface Sclerites in Gorgonians (Coelenterata, Octocorallia)
2. New record of Sarcophyton cornispiculatum Verseveldt, 1971 (Octocorallia: Alcyonacea: Alcyoniidae) in India, from the Andaman Islands
3. A revision of the genus Sarcophyton Lesson (Octocorallia, Alcyonacea);Verseveldt;Zool. Verhandel.,1982
4. A redescription of Alcyonium agaricum Stimpson with a generic placement in Sarcophyton (Coelenterata: Octocorallia);Alderslade;Precious Corals Octocorals Res.,1993
5. New species of soft corals (Coelenterata: Octocorallia) from the Laccadive Archipelago;Alderslade;Beagle,1991