Akt-mediated foxo1 inhibition is required for liver regeneration

Author:

Pauta Montse12,Rotllan Noemi234,Fernández-Hernando Ana2,Langhi Cedric5,Ribera Jordi1,Lu Mingjian67,Boix Loreto8,Bruix Jordi8,Jimenez Wladimiro19,Suárez Yajaira234,Ford David A.5,Baldán Angel5,Birnbaum Morris J.6,Morales-Ruiz Manuel19,Fernández-Hernando Carlos234

Affiliation:

1. Department of Biochemistry and Molecular Genetics, Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS); Centro de Investigaciones Biomédicas en Red en Enfermedades Hepáticas y Digestivas (CIBERehd); Barcelona Spain

2. Departments of Medicine and Cell Biology, Leon H. Charney Division of Cardiology; New York University School of Medicine; New York NY

3. Vascular Biology and Therapeutics Program; Yale University School of Medicine; New Haven CT

4. Integrative Cell Signaling and Neurobiology of Metabolism Program, Section of Comparative Medicine and Department of Pathology; Yale University School of Medicine; New Haven CT

5. Edward A. Doisy Department of Biochemistry & Molecular Biology and Center for Cardiovascular Research; Saint Louis University; St. Louis MO

6. Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine; University of Pennsylvania; Philadelphia PA

7. Lilly China Research and Development Center; Shanghai People's Republic of China

8. Barcelona Clinic Liver Cancer Group, Liver Unit, Hospital Clínic of Barcelona; University of Barcelona, IDIBAPS, CIBERehd; Barcelona Spain

9. Department of Physiological Sciences I; University of Barcelona; Barcelona Spain

Funder

Ministerio de Economía y Competitividad

Fundacio La Marato de TV3-2013

National Institutes of Health

Foundation Leducq Transatlantic Network of Excellence in Cardiovascular Research

Publisher

Wiley

Subject

Hepatology

Reference59 articles.

1. Liver regeneration;Fausto;Hepatology,2006

2. Liver regeneration;Michalopoulos;Science,1997

3. Experimental pathology of liver resection;Higgins;Arch Pathol,1931

4. Liver resections in cirrhotic patients: a Western experience;Bismuth;World J Surg,1986

5. Liver regeneration after living donor transplantation: adult-to-adult living donor liver transplantation cohort study;Olthoff;Liver Transpl,2015

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