The Upregulation of PI3K/Akt and MAP Kinase Pathways is Associated with Resistance of Microtubule-Targeting Drugs in Prostate Cancer

Author:

Liu Zhi1,Zhu Guangjing1,Getzenberg Robert H.2,Veltri Robert W.1

Affiliation:

1. The James Buchanan Brady Urological Institute; The Johns Hopkins University School of Medicine; Baltimore Maryland 21287

2. GTx Inc.; Memphis Tennessee 38103

Funder

National Cancer Institute

National Institutes of Health

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference40 articles.

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2. MDR1 (ABCB1) polymorphisms: functional effects and clinical implications;Brambila-Tapia;Rev Invest Clin,2013

3. Taxol-requiring mutant of Chinese hamster ovary cells with impaired mitotic spindle assembly;Cabral;J Cell Biol,1983

4. Conserved oncogenic behavior of the FAM83 family regulates MAPK signaling in human cancer;Cipriano;Mol Cancer Res,2014

5. MAP kinase signalling pathways in cancer;Dhillon;Oncogene,2007

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