Dual Targeting of G9a and DNA Methyltransferase‐1 for the Treatment of Experimental Cholangiocarcinoma

Author:

Colyn Leticia1,Bárcena‐Varela Marina1,Álvarez‐Sola Gloria12,Latasa M. Ujue1,Uriarte Iker12,Santamaría Eva12,Herranz Jose M.12,Santos‐Laso Alvaro3,Arechederra Maria1,Ruiz de Gauna Mikel4,Aspichueta Patricia4ORCID,Canale Matteo5,Casadei‐Gardini Andrea6,Francesconi Maria7,Carotti Simone78,Morini Sergio7,Nelson Leonard J.9,Iraburu Maria J.10,Chen Chaobo11ORCID,Sangro Bruno21213,Marin Jose J.G.214ORCID,Martinez‐Chantar Maria L.215ORCID,Banales Jesus M.23,Arnes‐Benito Robert16,Huch Meritxell16,Patino John M.17,Dar Altaf A.17,Nosrati Mehdi17,Oyarzábal Julen18,Prósper Felipe1319,Urman Jesus1320,Cubero Francisco Javier11ORCID,Trautwein Christian21,Berasain Carmen1213ORCID,Fernandez‐Barrena Maite G.1213ORCID,Avila Matias A.1213ORCID

Affiliation:

1. Hepatology Program CIMAUniversity of Navarra Pamplona Spain

2. CIBERehdInstituto de Salud Carlos III Madrid Spain

3. Department of Liver and Gastrointestinal Diseases Biodonostia Health Research Institute, Donostia University Hospital, Ikerbasque Donostia‐San Sebastian Spain

4. Biocruces Health Research Institute Department of Physiology University of the Basque Country Leioa Spain

5. Biosciences Laboratory Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS Meldola Italy

6. School of Medicine Vita‐Salute San Raffaele University and Unit of OncologyIRCCS San Raffaele Scientific Institute Milan Italy

7. Unit of Microscopic and Ultrastructural Anatomy University Campus Bio‐Medico Rome Italy

8. Predictive Molecular Diagnostic Division Pathology Department Campus Bio‐Medico University Hospital Rome Italy

9. School of Engineering Institute of Engineering The University of Edimburgh Edimburgh United Kingdom

10. Department of Biochemistry and Genetics University of Navarra Pamplona Spain

11. Department of Immunology, Ophtalmology and ENT School of Medicine Complutense University Madrid Spain

12. Hepatology Unit Navarra University Clinic Pamplona Spain

13. Instituto de Investigaciones Sanitarias de Navarra IdiSNA Pamplona Spain

14. Experimental Hepatology and Drug Targeting (HEVEFARM) University of SalamancaIBSAL Salamanca Spain

15. Liver Disease Laboratory Center for Cooperative Research in Biosciences (CICbioGUNE) Basque Research and Technology Alliance (BRTA)Bizkaia Technology Park Derio Spain

16. Max Plank Institute of Molecular Cell Biology and Genetics Dresden Germany

17. California Pacific Medical Center Research Institute San Francisco CA

18. Molecular Therapies Program CIMAUniversity of Navarra Pamplona Spain

19. Oncohematology Program CIMAUniversity of Navarra Pamplona Spain

20. Department of Digestive Diseases Complejo Hospitalario de Navarra Pamplona Spain

21. Department of Internal Medicine III University HospitalRWTH Aachen Aachen Germany

Publisher

Wiley

Subject

Hepatology

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