A review on recent advances in assays for DNMT1: a promising diagnostic biomarker for multiple human cancers

Author:

Yu Yang12,Fu Wen3,Xie Yaxing2,Jiang Xue4,Wang Hong1,Yang Xiaolan2ORCID

Affiliation:

1. Department of Laboratory Medicine, QianWei People's Hospital, Leshan 614400, China

2. Key Laboratory of Medical Laboratory Diagnostics of the Education Ministry, College of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, China

3. Department of Thoracic Surgery, Chongqing University Cancer Hospital, Chongqing 400030, China

4. Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

Abstract

The abnormal expression of human DNA methyltransferases (DNMTs) is closely related with the occurrence and development of a wide range of human cancers.

Funder

Natural Science Foundation of Chongqing

Chongqing Science and Technology Commission

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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