New analytical method for the study of metabolism of swertiamarin in rats after oral administration by UPLC-TOF-MS following DNPH derivatization-Reference-Cited by-全球学者库

New analytical method for the study of metabolism of swertiamarin in rats after oral administration by UPLC-TOF-MS following DNPH derivatization

Published:2015-01-21 Issue:8 Volume:29 Page:1184-1189
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomed. Chromatogr.

Author:

Wu Xiuhong¹,Tang Shuhan²³,Jin Yan³,Zhang Yan³,Hattori Masao²,Wang Xijun¹,Zhang Hailong⁴,Wang Zhigang¹²

Affiliation:

1. National TCM Key Laboratory of Serum Pharmacochemistry; Department of Pharmaceutical Analysis; Heilongjiang University of Chinese Medicine; Heping Road 24 Harbin 150040 China

2. Institute of Natural Medicine; University of Toyama; 2630 Sugitani Toyama 930-0194 Japan

3. Harbin Children Hospital; Youyi road 57 Harbin China

4. School of Pharmacy; Health Science Center; Xi'an Jiaotong University; Shaanxi 710061 China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference19 articles.

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3. Metabolism of swertiamarin from Swertia japonica by human intestinal bacteria;el-Sedawy;Planta Medica,1989

4. Transformation of aucubin to new pyridine monoterpene alkaloids, aucubinines A and B, by human intestinal bacteria;Hattori;Phytotherapy Research,1990

5. Studies on neurosteroids XIX. Development and validation of liquid chromatography-tandem mass spectrometric method for determination of 5alpha-reduced pregnane-type neurosteroids in rat brain and serum;Higashi;Journal of Chromatography B,2007

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