Long‐term survival of participants in the CENTAUR trial of sodium phenylbutyrate‐taurursodiol in amyotrophic lateral sclerosis

Author:

Paganoni Sabrina12ORCID,Hendrix Suzanne3,Dickson Samuel P.3,Knowlton Newman3,Macklin Eric A.4,Berry James D.1,Elliott Michael A.5,Maiser Samuel6,Karam Chafic7,Caress James B.8,Owegi Margaret Ayo9,Quick Adam10,Wymer James11,Goutman Stephen A.12ORCID,Heitzman Daragh13,Heiman‐Patterson Terry D.14,Jackson Carlayne E.15,Quinn Colin16,Rothstein Jeffrey D.17,Kasarskis Edward J.18,Katz Jonathan19,Jenkins Liberty19,Ladha Shafeeq20,Miller Timothy M.21,Scelsa Stephen N.22,Vu Tuan H.23,Fournier Christina N.24,Glass Jonathan D.24,Johnson Kristin M.25,Swenson Andrea26,Goyal Namita A.27,Pattee Gary L.28,Andres Patricia L.29,Babu Suma1,Chase Marianne1,Dagostino Derek1,Hall Meghan20,Kittle Gale20,Eydinov Matthew1,McGovern Michelle1,Ostrow Joseph1,Pothier Lindsay1,Randall Rebecca20,Shefner Jeremy M.20,Sherman Alexander V.1,St Pierre Maria E.1,Tustison Eric1,Vigneswaran Prasha1,Walker Jason1,Yu Hong1,Chan James4,Wittes Janet30,Yu Zi‐Fan30,Cohen Joshua31,Klee Justin31,Leslie Kent31,Tanzi Rudolph E.1,Gilbert Walter32,Yeramian Patrick D.31,Schoenfeld David4,Cudkowicz Merit E.1

Affiliation:

1. Sean M. Healey & AMG Center for ALS & the Neurological Clinical Research Institute Massachusetts General Hospital, Harvard Medical School Boston Massachusetts

2. Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital Harvard Medical School Boston Massachusetts

3. Pentara Corporation Millcreek Utah

4. Department of Medicine, Biostatistics Center Massachusetts General Hospital, Harvard Medical School Boston Massachusetts

5. Swedish Neuroscience Institute Seattle Washington

6. Departments of Neurology and Medicine Hennepin Healthcare Minneapolis Minnesota

7. Department of Neurology Oregon Health & Science University Portland Oregon

8. Department of Neurology Wake Forest School of Medicine Winston‐Salem North Carolina

9. Department of Neurology University of Massachusetts Memorial Medical Center Worcester Massachusetts

10. Department of Neurology The Ohio State University College of Medicine Columbus Ohio

11. Department of Neurology University of Florida College of Medicine Gainesville Florida

12. Department of Neurology University of Michigan Ann Arbor Michigan

13. Texas Neurology Dallas Texas

14. Department of Neurology, Lewis Katz School of Medicine Temple University Philadelphia Pennsylvania

15. Department of Neurology The University of Texas Health Science Center at San Antonio San Antonio Texas

16. Department of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia Pennsylvania

17. Brain Science Institute and Department of Neurology Johns Hopkins University Baltimore Maryland

18. Department of Neurology University of Kentucky College of Medicine Lexington Kentucky

19. California Pacific Medical Center Research Institute and Forbes Norris MDA/ALS Research and Treatment Center San Francisco California

20. Department of Neurology, Gregory W. Fulton ALS Center Barrow Neurological Institute Phoenix Arizona

21. Department of Neurology Washington University School of Medicine in St. Louis St. Louis Missouri

22. Department of Neurology, Mount Sinai Beth Israel Icahn School of Medicine at Mount Sinai New York New York

23. Department of Neurology University of South Florida Morsani College of Medicine Tampa Florida

24. Departments of Neurology and Pathology Emory University School of Medicine Atlanta Georgia

25. Department of Neurology Ochsner Health System New Orleans Louisiana

26. Department of Neurology University of Iowa Carver College of Medicine Iowa City Iowa

27. Department of Neurology University of California, Irvine School of Medicine Irvine California

28. Neurology Associates Lincoln Nebraska

29. Independent Consultant Nobleboro Maine

30. Statistics Collaborative, Inc. Washington District of Columbia

31. Amylyx Pharmaceuticals, Inc. Cambridge Massachusetts

32. Harvard University Cambridge Massachusetts

Funder

Amyotrophic Lateral Sclerosis Association

Publisher

Wiley

Subject

Physiology (medical),Cellular and Molecular Neuroscience,Neurology (clinical),Physiology

Reference37 articles.

1. Amyotrophic Lateral Sclerosis

2. The role of managed care professionals in improving care for patients with ALS

3. A Controlled Trial of Riluzole in Amyotrophic Lateral Sclerosis

4. Dose-ranging study of riluzole in amyotrophic lateral sclerosis

5. Real‐world evidence of riluzole effectiveness in treating amyotrophic lateral sclerosis;Andrews JA;Amyotroph Lateral Scler Frontotemporal Degener.,2020

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